Tadaflo 5mg tablet contains the active ingredient Tadalafil. It is a medication primarily used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH) symptoms. Erectile dysfunction is an inability to keep an erection firm enough for sexual activity. BPH is a condition characterized by men's prostate gland enlargement. This medication is not used in women and individuals under 18. This medication can enhance sexual performance and improve overall sexual satisfaction. By facilitating the ability to achieve and maintain an erection, it can increase confidence and reduce anxiety related to sexual activity.
Tadaflo 10mg tablet should not be taken if you currently use any form of nitrate-related medication ( used for angina or heart conditions). This medication is unsuitable for individuals with certain cardiovascular conditions, including recent heart attacks, unstable angina, severe heart failure, uncontrolled high blood pressure, or stroke within the past six months. Do not drink alcohol and grapefruit juice while taking Tadaflo 10mg tablet. Talk to your physician if you are intolerant to sugars, as this medicine contains lactose. You need to inform your physician about any serious heart disorders, low or high blood pressure, vision problems, sickle cell anemia, liver disorders, kidney disorders, or a recent heart attack if you have.
For detailed information on how to avoid Tadaflo 10mg tablet inform your doctor if you are intolerant to any six-month dosage information seek consult with your doctor. This medicine can cause some side effects such as headache, flushing, upset stomach,blurred vision,trouble sleeping, hot/cold/fat/Headache, vision changes, drowsiness,For detailed information on how to take Tadaflo 10mg tablet inform your doctor if you are taking any form of multivitamin or mineral supplement. Do not take more than the prescribed dose of this medicine in a 24 hours. Your doctor will decide if you are to continue taking this medication or if you should continue taking it gradually. Do not stop taking this medicine without consulting your doctor. Consulting a healthcare professional is essential for the safe use of this medicine.This medicine.com offers only a selection of medicines. Some of these medicines may interact with each other, lower the diagnosis and management cost, and could cause serious side effects. You should not take this medicine if you are allergic to any medicines. Before taking this medicine, inform your doctor if you have kidney problems, vision problems, sickle cell anemia, liver disorders, vision problems, stomach ulcers, a heart attack, heart failure, pcos, penile bleeding, enlarged prostate, an enlarged uterus, recent history of heart attack, diabetes, porphyria, gastrointestinal symptoms, stomach ulcers, or use recreational drugs and if you are taking any other medication. This medicine should not be taken if you are using any herbal supplements or medicines. Other medicines and foods may interact with this medicine. Before undergoing any medical treatment or medicine initiation, you should tell your doctor if you have any conditions, including heart disease, liver or kidney problems, heart disease, liver or kidney impairment, digestive or liver problems, a history of epilepsy, retinitis pigmentosa, stomach ulcers, heart problems, heart disease, a heart attack, heart failure, Peyronie's disease, or heart rhythm problems. This medicine should not be used during pregnancy or breastfeeding unless definitely directed to do so by a healthcare professional. Tell your doctor if you are pregnant, may become pregnant or are breastfeeding. Also, remember that your doctor will discuss the most appropriate treatment for you based on your medical condition, response to treatment, and other medications you are taking. This medicine may interact with certain medications, vitamins and herbal products. Discuss with your doctor if you are using any herbal supplements or medicines.
This document contains non-prescription products that are used to treat erectile dysfunction. Non-prescription products that you can review periodically.Do not take this medicine if you have an allergy to any of the ingredients or to any of the following: any of the ingredients listed at the end of this page.
Some non-prescription products contain propylene glycol monostear or macrogol stearate.
Some products contain lactose. Some contain magnesium stearate.
Some products contain sucrose or sucroseol stearate.
Some products contain alcohol.
Some products contain starch or lactose. Some products contain iron.
Some products contain calcium. Some products contain calcium sulfate.
Some products contain calcium, magnesium, or zinc.
1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
Cialis (tadalafil) can interact with certain foods and beverages, including grapefruit, grapefruit juice, and alcohol, increasing the levels of tadalafil in your blood by>. Avoid combining these two ingredients, as they may increase the risk of side effects.
5.Other Antibiotics (e.g.,,,):: While Cialis can enhance the blood pressure-lowering effects of the medications,, combining it with antifungals, antibiotics, or high-fat meals may worsen side effects.
Cialis (tadalafil) can cause a side effect called dizziness or lightheadedness, followed by a side effect called dizziness or tinnitus (ringing in the ears). If you take Cialis with nitrates or recreational "poppers', do not take this medication.
Phosphodiesterase (PDE-5) inhibitors, including tadalafil (Cialis®) and vardenafil (Levitra®), are effective for the treatment of erectile dysfunction (ED) and pulmonary arterial hypertension (PAH), respectively. The most commonly prescribed PDE-5 inhibitors are those used for benign prostatic hyperplasia (BPH) and benign prostatic hyperplasia- (BPH-). These medications are associated with significant adverse effects that necessitate close supervision.
The global PDE-5 inhibitor market size is estimated to reach USD 1.14 billion in 2023, increasing at a CAGR of 6.5% from 2024 to 2030[1][4]. The market is driven by the increasing prevalence of erectile dysfunction (ED) and pulmonary arterial hypertension (PAH)[5].
The market for PDE-5 inhibitors is diverse, covering different regions and companies:
Several key factors contribute to the market's growth. The increasing prevalence of ED and the increasing incidence of BPH and PAH are associated with the rise of online services and applications. Companies are seeking to improve their reach and increase their customer service customer satisfaction customer-centricity[2][4]. Additionally, the aging population and growing awareness of erectile dysfunction have boosted the demand for PDE-5 inhibitors[4][5].
Despite the growth prospects, the market faces restraints due to several factors. The healthcare system is in the midst of a global pandemic, and the increasing availability of generic and alternative medications is likely to restrain the market growth[2]. Additionally, the high costs of medications, including the cost of insurance and the limited availability of generic and affordable alternatives, are a major cause for the market's price stability[5].
Government initiatives are expected to enhance the regulatory environment for PDE-5 inhibitors, which is expected to significantly impact market growth. The regulatory environment, including the U. S. Food and Drug Administration (FDA), the European Medicines Agency (EMA) and the U. Food and Drug Administration (FDA), is a major factor that is likely to limit the market's growth[2][4].
Several challenges remain before the market's growth can be assured. The high cost of medications, including the inability of the market to meet growing demand, the shortage of generic and affordable options, the difficulty in obtaining and maintaining regulatory approval, and the regulatory atmosphere surrounding the COVID-19 pandemic have all contributed to market instability[2][4].
The market for PDE-5 inhibitors is influenced by various factors, including regulatory, healthcare system, market stability, competition, demand from generic and affordable sources, and consumer preferences. However, the regulatory environment and regulatory challenges surrounding the COVID-19 pandemic are likely to hinder the market's growth. As a result, the market's growth is likely to slow due to restraints on market expansion and the increasing preference for generic and affordable medications[1][5].
Please refer to the table below to learn more about regulatory and market opportunities.
1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.
2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/
3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf
4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36
5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs
C96827C96827, Oxford Chemicals Limited.https://www. OX.gov.in/CDSCO/Drugs
OX.in/CDSCO/Drugshttps://www.ox.in/CDSCO/Drugs
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